7707: Use of clear aligners for the treatment of dental malocclusion in individuals with Osteogenesis Imperfecta Types III and IV
Misalignment of teeth may interfere with oral hygiene, gum health, jaw function, opening of the jaw, chewing, breathing, and speech. It can also affect the shape of your face, mouth and overall quality of life. There is very little information on the appropriate treatment for teeth misalignment in OI.
The purpose of this study is to determine if it is safe to use Invisalign clear aligners in correcting the misalignment of teeth in people with OI. Clear aligners are transparent plastic trays that are designed to fit over your teeth. With each new tray, teeth are moved a little at a time until they reach the desired position. We plan to have approximately 57 people take part in this study. If you take part in this study, you will be asked to come to a participating site for up to a total of 15 study visits over a course of 2 years and 4 months (or 28 months).
You may be eligible to participate if you:
- are between ages 12 – 40
- have OI type III or IV
- have had no prior orthodontic treatment
How to participate:
In order to participate, you must contact the study coordinator of any of the participating institutions by phone or by e-mail. Please use the information below to inquire about participation:
National Institutes of Dental Craniofacial Research (Bethesda, Maryland)
Contact: Danielle Elangue MHA, MBA, RN, Research Nurse Specialist ( C )
301-451-9733 | danielle.elangue@nih.gov
University of California at Los Angeles (Los Angeles, California)
Contact: Sarah Gaunt, Clinical Research Coordinator
310 -206 -7176 | sgaunt@mednet.ucla.edu
Disclaimer: The OI Foundation is not involved in the design or management of this research, and as such, is neither endorsing nor supporting this study. The mission of the OIF is to keep the OI community informed of all relevant studies. This information is made available as a service to the OI community. We are available to answer questions on this or any other research announcement. Please contact the OI Foundation at (301) 947-0083 or bonelink@oif.org if you have any questions.
