IntOI 2020+1: Virtual International OI Meeting
Early-Stage Investigator Symposium
September 9, 2021 from 11:00am-4:30pm, Eastern Standard Time
The 2021 Virtual International OI Meeting on September 9, 2021 from 11am-4pm, Eastern Standard Time is an interim International OI meeting pending the return of in-person meetings, with the postponement of the International OI meeting to 2022 in Sheffield, UK. Click here to learn about the 2022 meeting. The presentation focus is on engaging early-stage investigators.
Meeting registration is open to scientific and medical professionals interested in OI research.
Agenda:
11:00-11:10am ET
Welcome Remarks
Tracy Hart – OI Foundation Chief Executive Officer
Joan Marini, MD, PhD- National Institutes of Health
11:10-11:40am ET
Six New Technologies and What They Are Teaching Us About Bone
Prof Natalie A Sims, PhD, St Vincent’s Institute of Medical Research
Presentations will be 10 minutes followed by 5 minutes for discussion.
11:40-11:55am ET
A heterozygous gain-of-function variant in KIF5B causes osteogenesis imperfecta by disrupting the Golgi-primary cilia axis
Ronit Marom, MD, PhD, Baylor College of Medicine
Nadia Garibaldi, PhD, University of Pavia
Bone Tissue and Osteoblasts from X-linked Type XVIII OI with Defects in Regulated Intramembrane Proteolysis Have Distinct Features
Ali Zarei, PhD, National Institutes of Health
12:25-12:40pm ET
Development of a human bone-derived organoid model of Osteogenesis imperfecta
Timothée Ndarugendamwo, University of Zürich
Presentations will be 10 minutes followed by 5 minutes for discussion after each presentation.
12:40-12:55pm ET
Localized Chondro-ossification Leads to Progressive Joint Deformities in a Mouse Model of Recessive Osteogenesis Imperfecta
Joohyun Lim, PhD, Baylor College of Medicine
In-Hong Kang, PhD, The Medical University of South Carolina
Sclerostin antibody enhances peri-implant osseointegration in an Osteogenesis Imperfecta mouse model
Hsiao Sung, University of Michigan
1:25pm-1:40pm BREAK
1:40-1:45pm ET
Zebrafish tmem38b Knock out unveils the in vivo role of Trimeric Intracellular Cation (TRIC) channel B on cell homeostasis
Francesca Tonelli, PhD, University of Pavia
Transcriptome profiling of S2P mutant fibroblasts to unravel the pathomechanism and molecular signatures of X-linked MBTPS2 Osteogenesis Imperfecta
Pei Jin Lim, PhD, University of Zurich
Studies of OI Patient and Murine Osteoblasts to Investigate Phenotypic Variability of Dominant Osteogenesis Imperfecta
Milena Jovanovic, PhD, National Institutes of Health
1:55-2:00pm ET
Bone toughness changes during skeletal growth in brittle osteogenesis imperfecta bone. How and why?
Anxhela Docaj, The City College of New York
2:00-2:05pm ET
Osteoblasts derived from human fibroblasts via induced mesenchymal stem cells as a potential cell model for Osteogenesis Imperfecta
Lauria Claeys, Amsterdam UMC
2:05-2:10pm ET
Stress reduction by 4-PBA treatment improves bone phenotypes in the Aga2 mouse model of Osteogenesis Imperfecta
Jennifer Zieba, PhD, University of California-Los Angeles
2:10-2:20pm ET
Discussion of Short Talks
2:20-2:50pm ET
Clinical Studies Keynote: Pulmonary Studies
Cathleen Raggio, MD, Hospital for Special Surgery
Presentations will be 10 minutes followed by 5 minutes for discussion after each presentation
2:50-3:05pm ET
Effects of Neuraxial Analgesia on Post-Operative Pain Scores in Children with Osteogenesis Imperfecta
Nicholas Bohannon, University of Nebraska Medical Center
Multicenter Series of Deformity Correction using Guided Growth in the Setting of Osteogenesis Imperfecta
Jeanne Franzone, MD, Nemours Alfred I. duPont Hospital for Children
Bone Assessment of Individuals with Osteogenesis Imperfecta using Non-Invasive Fiber Optic Spectroscopy
William Querido, PhD, Temple University
3:35pm-3:40pm ET
Growth Plate Biomarkers in Patients with Osteogenesis Imperfecta
Ricki Carroll, MD, Nemours Alfred I. duPont Hospital for Children
Intravenous Bisphosphonates are Associated with Improved Final Height Among Children with Osteogenesis Imperfecta
Marie-Eve Robinson, University of Ottawa
Risk of eye diseases in Osteogenesis Imperfecta – A register-based cohort study
Marie Louise Lyster, University of Southern Denmark, SDU
3:50pm-3:55pm ET
Missing and unerupted teeth in Osteogenesis Imperfecta: A genetic analysis
Taqi Doaa, McGill University
3:55-4:00pm ET
The Creation of an Individualized School Plan for Optimal Inclusion of Students with OI
Jessica Chemtov, McGill University/Shriners Hospital for Children-Canada
Galil Osman, McGill University/Shriners Hospital for Children-Canada
4:00-4:10pm ET
Discussion for Clinical OI—Short Talks
4:10pm-4:15pm
Closing remarks
Meeting Chair Joan Marini, MD, PhD, National Institutes of Health
CLICK HERE TO REGISTER
For questions, please contact Erika Carter at ecarter@oif.org.
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